Graim Lab

Tools

We develop tools for many genomic applications. GraimLab GitHub and highlights of repositories, tutorials, and guides for these tools are shared below.

TODO ExoGAN

ExoGAN designs precision receptor-targeting peptides using quantum chemically predicted features to understand physiochemical interaction dynamics, increasing the efficacy of designed point-target exosomal pharmaceutics.

TODO FREYA Pipeline

The FREYA analytic framework streamlines cross-species tumor analyses and provides a comprehensive suite of tools that encompass conventional human analyses and new dog-centric approaches, seamlessly integrating the two.

TODO PhyloFrame

An ML approach for generating ancestry unbaised genetic signatures.

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TODO Canine Mammary Tumor Dataset

RNA-seq data of the 89 canine mammary samples from Graim et al 2021.

TODO PLATYPUS

A semi-supervised multi-view machine-learning framework that integrates multiple biological priors and multiple data sources with mismatched samples.

TODO HOCUS

A unified analytical framework for patient stratification that uses a community detection technique to extract subtypes from sparse patient measurements.