Graim Lab

Tools

We develop tools for many genomic applications. Repositories, tutorials, and guides for these tools are shared below.

ExoGAN

ExoGAN designs precision receptor-targeting peptides using quantum chemically predicted features to understand physiochemical interaction dynamics, increasing the efficacy of designed point-target exosomal pharmaceutics.

FREYA Pipeline

The FREYA analytic framework streamlines cross-species tumor analyses and provides a comprehensive suite of tools that encompass conventional human analyses and new dog-centric approaches, seamlessly integrating the two.

PhyloFrame

An ML approach for generating ancestry unbaised genetic signatures.

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Canine Mammary Tumor Dataset

RNA-seq data of the 89 canine mammary samples from Graim et al 2021.

PLATYPUS

A semi-supervised multi-view machine-learning framework that integrates multiple biological priors and multiple data sources with mismatched samples.

HOCUS

A unified analytical framework for patient stratification that uses a community detection technique to extract subtypes from sparse patient measurements.